Renal Transplant News

Transplant News Issue 19

Nephrologist’s Note: Diabetes and Kidney Disease

Chandra B. Chandran, M.D.By Chandra B. Chandran, M.D., Nephrologist, Fair Lawn, NJ

Nephrologist’s Note features timely information provided by physicians in the greater tri-state area.

Diabetes is fast becoming the epidemic of the 21st Century. According to the American Diabetes Association, some 1.3 million new cases are diagnosed each year. Diabetes can cause a variety of serious complications including kidney failure. With the attentive care of a primary care physician and a nephrologist, proactive patients with good control of their diabetes may be able to delay the onset of end stage renal disease. For many with diabetes, the organ transplant options available today can both prolong and improve the quality of life.

Diabetes is a chronic illness that often causes a steady decline in renal function once the kidney is affected. There are two paths of treatment for end stage renal disease associated with diabetes — organ transplantation and dialysis. I recommend that patients explore both options early in the course of their disease, usually when the kidney function gets below 25 percent, so they are prepared to make educated choices as the effects of diabetes advance.

People with diabetes have several transplant options. They may receive a kidney transplant or they may be eligible to receive both a kidney and pancreas transplant. A pancreas transplant is perhaps the best thing that can happen for a person with Type I diabetes. A successful pancreas transplant essentially cures the recipient of his or her diabetes. Patients no longer need to check blood sugar levels or inject insulin. A pancreas transplant prevents any further complications of diabetes and in some cases can even reverse mild symptoms. Because the human body has only one pancreas, the transplanted organ must be provided by a deceased donor.

If a patient’s kidney function falls below 10 - 15 percent, he or she should begin dialysis treatments to remove toxins from the blood stream or receive a kidney transplant to replace the failing organ. Unfortunately, the high risk complications of diabetes can advance more quickly once the patient begins dialysis. If a patient is fortunate enough to receive a kidney transplant before dialysis is necessary or shortly after dialysis begins, they can avoid high rates of infection at the catheter, graft or fistula site and heart disease that often results from prolonged dialysis. A kidney transplant can come from a living donor or a deceased donor.

Another transplant option offers a solution to both diabetes and any resulting kidney disease. Patients can receive a kidney and a pancreas transplant during the same surgery, or they can receive a pancreas transplant after their successful kidney transplant.

Regardless of the treatment option patients choose, it should be part of an aggressive health plan that includes close monitoring of all the body systems. It is vital that people with diabetes and their nephrologists work together to control blood pressure and cholesterol levels. Daily exercise should be a part of every patient’s health care plan. Smoking should be avoided.

To learn more about the treatment for kidney disease, visit the National Kidney Foundation web site at www.kidney.org.

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